Wrinkle Freeze Cream With 20% Argireline & Swiss Apple Stem Cell Extract

Experience the powerful anti-aging benefits of Anni Mateo’s Wrinkle Freeze Cream, formulated with 20% Argireline, Swiss Apple Stem Cell Extract, Lupine Peptides, Botopical®, and Vitamins A, B, C, D, and E.

This potent formula is designed to combat all signs of aging effectively. The blend of 20% Argireline (Acetyl hexapeptide-3), Lupine peptides, Swiss Apple stem cell extract, and Botopical® delivers a Botox-like effect, relaxing the skin and reducing wrinkles.

The active ingredients include a mix of peptides, vitamins, natural antioxidants from apple and berries, Swiss Apple stem cell extracts and a plethora of other high-tech ingredients

In addition to these key ingredients, the cream includes a range of other active components at high concentrations. Apple extracts, tomato, and red berries, along with vitamins A, B, C, D, and E, hyaluronic acid, MSM, hydrolyzed wheat proteins, hydrolyzed oats, and squalane, provide intensive anti-aging and antioxidant properties.

The antioxidants in this cream detoxify and neutralize free radicals caused by air pollution, sunlight, alcohol, cigarette smoke, and stress. Lycopene from tomatoes protects the skin’s collagen and balances sebum production.

Formulated with mostly food-grade, natural ingredients, this cream is free of petroleum products, parabens, silicones, fillers, synthetic fragrances, colors, and harsh preservatives. It is suitable for all skin types and is particularly effective for addressing expression wrinkles, and dry, sensitive, and stressed skin. Ideal for both day and night use, it is perfect for men and women alike.

Packed with a high concentration of proven actives and potent anti-aging and wrinkle-fighting ingredients, this cream includes hydrolyzed Lupine peptides, Botopical®, vitamin A palmitate, vitamin C ester, hydrolyzed wheat and oats proteins, hyaluronic acid, MSM, niacinamide, and pro-vitamin B5. These components aid in cell repair and renewal, promoting even skin tone and clearing acne and inflamed skin.

It also promotes 24-hour hydration thanks to hyaluronic acid, squalane, vegetable glycerine, argan oil, and a unique combination of pure oils and butters.

What the active ingredients do

BOTOPICAL®, a BOTOX®-like cosmetic solution and a non-aggressive alternative to reduce expression wrinkles. Rich in organic compounds from rye, Botopical favours the relaxation of subcutaneous muscles, thus correcting wrinkles caused by facial movements.

They offer a long-lasting tensor effect by stimulating the mechanical cell functions involved in the modulation of skin tension forces and reducing the phenomena of micro tensing to visibly smooth expression lines. Botopical relaxes the features while at the same time conversing the natural mobility of the face.

Botopical stimulates the formation of mechano-receptors. Tested at 0.25 % on normal human fibroblasts, Botopical stimulates the synthesis of integrin α2 ß 1 by 20 % and boosts the synthesis of vinculin, a marker of focal adhesions, by 28%.

Botopical increases the mechanical resistance of the skin. Tested at 0.50% on normal human fibroblasts, Botopical led to a 62% increase in the synthesis of a-SMA fibres, responsible for the retractile forces of fibroblasts. Moreover, the in vivo tests have shown the anti-wrinkle properties of Botopical at 4% after 56 days of treatment on the level of the crow’s foot and the nasolabial fold in 72% and 78% of volunteers, respectively.

ARGIRELINE (Acetyl hexapeptide-3): Argireline works through a unique mechanism which relaxes facial tension leading to a reduction in superficial facial lines and wrinkles with regular use. Argireline has been shown to moderate excessive catecholamines release. Anti-age hexapeptide developed with combinatorial chemistry and high throughput screening techniques.

It reduces the severity of wrinkles around the eyes, up to 17% after 15 days of treatment and up to 27% after 30 days of treatment. It reduces the depth of wrinkles on the face caused by the contraction of muscles of facial expression, especially in the forehead and around the eyes. It prevents skin aging induced by repeated facial movements caused by excessive catecholamine release.

Argireline can be incorporated in cosmetic formulations such as emulsions, gels, serums, etc., where removing deep lines or wrinkles in the forehead or around the eye area is desired. The recommended use level is 3-10% of the solution to obtain significant anti-wrinkle activity. Popular Botox-alternative wrinkle treatments on the market use as much as 15% Argireline. However, this cream contains 20%.

LUPINE PEPTIDES: Lupine peptides is a blend of Penta- and Hexa- peptides derived from lupin flower protein that works as an MMP inhibitor, thus preventing MMP activity following exposure of the skin to sunlight. By doing this, the lupine peptides blend prevents collagen and elastin (the main proteins making up connective tissue) breakdown catalysed by MMP activity, helping to renew the skin’s outer layer, reduce the depth of wrinkles and stimulating the production of collagen & elastin, giving the skin a younger look.

SWISS APPLE STEM CELL EXTRACT: Swiss Apple stem cell extract has garnered attention for its regenerative properties, similar to animal stem cells. These plant stem cells can stimulate and regenerate tissues after injury, making them a focus in cosmetic development and skin studies. One study found that incubating human fibroblasts with 2% stem cell extract reversed aging symptoms by upregulating genes essential for cellular growth and increasing the antioxidant enzyme hemeoxygenase-1.

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