Argireline (Acetyl hexapeptide-3) peptide solution for the reduction of expression wrinkles 

Mode of action: When a person frowns, neurotransmitters are released to the synapses, which make the muscle receive a signal which tells it to move. The final stages of this process, called exocytosis, involve using three proteins, also known as the SNARE complex.

Argireline inhibits this SNARE complex formation and catecholamine release, resulting in decreased facial wrinkles and demonstrated effectiveness against their development with regular use. In clinical studies of twice-a-day treatment, the severity of wrinkles around the eyes decreased up to 17% after 15 days and 27% following 30 days of treatment.

The Science: Argireline works through a unique mechanism which relaxes facial tension leading to a reduction in superficial facial lines and wrinkles with regular use. Argireline has been shown to moderate excessive catecholamines release.

Anti-age hexapeptide developed with combinatorial chemistry and high throughput screening techniques. It reduces the severity of wrinkles around the eyes, up to 17% after 15 days of treatment and up to 27% after 30 days of treatment. It reduces the depth of wrinkles on the face caused by the contraction of muscles of facial expression, especially in the forehead and around the eyes.

It prevents skin ageing induced by repeated facial movements caused by excessive catecholamine release. Argireline can be incorporated in cosmetic formulations such as emulsions, gels, serums, etc., where removal of deep lines or wrinkles in the forehead or around the eyes area is desired.